Dreamweaver takes a long time to connect and/or timestamp related functions do not work correctly. When you check the site FTP log, you can see that Dreamweaver is failing to create and remove the temporary XYIZNWSK folder (MKD XYIZNWSK and RMD XYIZNWSK). The functions you may be seeing problems with include Select Newer, Synchronize, and the warning when Getting and Putting older versions of files.
Note: This TechNote applies to Dreamweaver MX 2004 and earlier. The Synchronize and Select Newer features were redesigned in Dreamweaver 8 and the XYIZNWSK folder is no longer created by Dreamweaver. For more information, see "How synchronization works in Dreamweaver 8" (TechNote kb400972).