Occasionally, a user account can become corrupted and prevent the installer from accessing or creating the necessary files and folders. Create a different account, log in to the new account, and then try to install or run the Adobe application.
Mac OS 10.7 (Lion) and 10.8 (Mountain Lion)
Mac OS 10.5 (Leopard) and 10.6 (Snow Leopard)
Mac OS 10.4 (Tiger)
Mac OS 10.3 (Panther)
Mac OS 10.2 (Jaguar)