Adobe Captivate crashes and any unsaved work is lost if the project cache is cleared from Windows Explorer (Widows) or Finder (Mac OS). However, the saved projects open perfectly fine when you relaunch Adobe Captivate and reopen them.
Operating systems on which this issue can occur: Windows Vista, Windows 7, and Mac OS
Project cache is introduced in Adobe Captivate 5 to help you open the projects faster. While setting up your project, it's necessary to specify the folder to be used as cache in the project preferences. (Choose Edit > Preferences > Global > General Settings.)
Adobe recommends that you clear the project cache by clicking the Clear Cache button in Preferences. Contents of cache folder can also be deleted using Windows explorer (Windows) or Finder (Mac OS), but only after closing all open projects in Adobe Captivate.
Best practice: Clear the cache after completing a project and before beginning the next one.
If you observe any other issues with project cache, post a query on Adobe Captivate forum.