When you upgrade to the latest version of macOS 10.13.4 or launch a Creative Cloud application for the first time on the latest versions of macOS High Sierra, you may see a warning message that indicates Adobe software needs to be optimized for better performance. This is due to some 32-bit components that we are working to address in a future Creative Cloud update. Please note that no action is required from you at this time and your applications will still run as normal.
For more information, see 32-bit app compatibility with macOS High Sierra 10.13.4.
Adobe has tested the latest versions of Adobe Creative Cloud applications for reliability, performance, and user experience when installed on Intel-based systems running macOS High Sierra (version 10.13). The latest versions of all Creative Cloud products are compatible.