In the Essential Sound panel, select the clip type as Dialogue, Music, SFX, or Ambience.

To make the loudness level uniform throughout the clip, expand Unify Loudness and click Auto Match. The loudness level (in LUFS) to which Premiere Pro auto-matched your clip appears below the Auto Match button.

Add the audio clip to a track in a multitrack session.

Select the audio clip and in the Essential Sound panel, select the clip type as Dialogue.

Select the Repair check-box and expand the section.

Select the check-box for the property that you want to change, and use the slider to adjust the level of the following properties between 0 through 10:

• Reduce Noise: Reduce the level of unwanted noises in the background, such as studio floor sounds and microphone background noise, and clicks. The proper amount of noise reduction depends upon the type of background noise and the acceptable loss in quality for the remaining signal.
• Reduce Rumble: Reduce the rumble noise--very low-frequency noise that ranges below the 80-Hz range, for example, noise produced by a turntable motor or an action camera.
• DeHum: Reduce or eliminate Hum—noise consists of a single frequency, in 50-Hz range (common in Europe, Asia, and Africa) or 60-Hz range (common in North and South America).  For example, electrical interference due to power cables laid too close to the audio cables can use such noise. You can select the hum level depending on the clip.
• DeEss: Reduce harsh, high-frequency ess-like sounds. For example, sibilance in vocal recordings that cause s-sounds created by breathing or air movement between the microphone and the singer’s mouth. 
• Reduce Reverb: Reduce or remove the reverb from audio recordings. This option allows you to to use original recordings from various sources and make them sound like they're coming from the same environment. 

Add the audio clip to an empty track in a multitrack session.

Select the clip and in the Essential Sound panel, select the clip type as Dialogue.

Select the Clarity check-box and expand the section.

Select the check-box for the property that you want to change, and use the slider to adjust the level of the following properties between 0 through 10:

Dynamics: Change the impact of the recording by compressing or expanding the dynamic range of your recording. You can change the level from natural to focused.

EQ: Reduce or boost selected frequencies in your recording. You can choose from a list of EQ presets that you can use on your audio and adjust the amount using the slider. To change the settings of EQ preset, select Effects>Audio Effects>Graphic Equalizer to view the graphic equalizer that you can adjust during playback, and save the changes.

Enhance speech: Select the dialogue as Male or Female to process and enhance it at the appropriate frequency.

Add the audio clip to an empty track in a multitrack session.

Select the audio clip and choose Window > Essential Sound > SFX.

To set reverb effect, choose the Reverb check-box under Creative.

In the Preset box, select a Reverb preset that suits your needs.

Open or create a multitrack session containing the audio clip.

Use the Essential Sound panel to tag the content to its specific type. You can duck clips tagged as music and ambience.

Select the background (for example, music) clip in the timeline, then assign it the Music audio type in the Essential Sound panel.

Click the checkbox next to Ducking to enable auto-ducking.

When you enable ducking, Premiere Pro adds an Amplify Effect to the clip. Keyframes that are computed by the Auto Ducking algorithm are added to this effect's gain parameter so that they can easily be changed or removed without interfering with your other sound design. 

Set the following auto-ducking options:

• Duck Against: Select the icons for the audio content types you wish to duck against - Dialogue, Music, Sound Effects, Ambience, or un-tagged clips.
• Sensitivity: This parameter adjusts the threshold at which the ducking triggers.  Higher or Lower sensitivity settings result in fewer adjustments, but focus on maintaining a lower or louder music track, respectively.  Middle-range sensitivity values trigger more adjustments where the music comes in and out quickly between pauses in speech.
• Reduce By: This parameter selects how much to reduce the volume of your music clip.  Adjusting this setting to the right reduces the volume more dramatically, towards the left for more subtle volume adjustments.
  
• Fades: This parameter controls how quickly the volume adjustment occurs when triggered.  Faster fades are ideal when mixing fast music with fast speech while slower fades are more appropriate when ducking background music behind voiceover tracks.

Click Generate Keyframes to compute and set keyframes for the Amplify effect that has been added to the clip.

To create a preset for Dialogue, select Essential Sound panel and click the panel menu.

You can view the presets that are already available for Dialogue listed here. 

If you want to customize and create extra preset, you can choose the desired settings.  After you have selected the desired settings, click Save settings as a preset button next to the Presets dropdown.