Support for Mac OS X Mavericks (10.9) was introduced with Acrobat and Reader 10.1.8 and 11.0.04. As with any new support for a new OS, unexpected issues could appear. Adobe plans to fix any discovered problems in upcoming releases.
Acrobat or Reader stops responding after using the Find command.
Workaround: Use the Advance Search command (Shift+Cmd+F) instead of the Find command (Cmd+F).
Alternatively, you can also install a patch. More information on downloading and installing the patch is here.
Using certain features in Acrobat or Reader such as zoom, pan, and the Sign and Commenting Panes results in excessive battery usage. When the battery menu is opened, Acrobat and Reader are listed as "Apps Using Significant Energy."
Workaround: None. Fixes are scheduled for the next planned update.
Safari 7 (delivered with Mac OS X Mavericks 10.9) and Safari 6.1 block the Acrobat and Reader PDF plug-in the first time a domain or website tries to display a PDF. For more detail, see http://helpx.adobe.com/acrobat/kb/blocked-plugin-alert-safari-7.html.
Workaround: Click the "Blocked" message and choose Trust when the Trust dialog appears or trust the plug-in globally.