Both Acrobat 2017 and Acrobat are compatible with the new macOS High Sierra (10.13). Below are a few known issues. Adobe is trying to fix these issues in a future release.
When you upgrade to the latest version of macOS 10.13.4 or launch Acrobat or Acrobat Reader for the first time on the latest versions of macOS High Sierra, you may see a warning message that indicates Adobe software needs to be optimized for better performance.
This is due to some 32-bit components that Adobe is working to address in the future. Note that no action is required from you at this time and your applications will still run as normal.
For more information, see the following resources: