You can use a wide range of hardware inputs and outputs with Adobe Audition. Sound card inputs let you bring in audio from sources such as microphones, tape decks, and digital effects units. Sound card outputs let you monitor audio through sources such as speakers and headphones.

When you configure inputs and outputs for recording and playback, Adobe Audition can use these kinds of sound card drivers:
In Windows, ASIO drivers support professional cards and MME drivers typically support standard cards.
In Mac OS, CoreAudio drivers support both professional and standard cards.
ASIO and CoreAudio drivers are preferable because they provide better performance and lower latency. You can also monitor audio as you record it and instantly hear volume, pan, and effects changes during playback.
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Note:
In the Multitrack Editor, you can override the defaults for specific tracks. See Assign audio inputs and outputs to tracks.
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Choose a Sample Rate for the audio hardware. (For common rates for different output mediums, see Understanding sample rate.)
Note:
By default, Adobe Audition controls ASIO sound cards while playing or monitoring audio. If you want to access the card in another application, select Release ASIO Driver In Background. (Audition still controls the card while recording to avoid having recordings suddenly stop.)
In network environments, Audition preferences are stored with each user account. For editing, interface, and other preferences, this creates a customized experience for each user. Audio hardware preferences, however, should typically remain consistent on a given machine, ensuring that inputs and outputs on the installed audio interface are available in Audition.
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To instead duplicate hardware settings from one machine to others, search for and copy the MachineSpecificSettings.xml file.
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This procedure also sets default outputs for the Master track in the Multitrack Editor. To override the defaults, see Assign audio inputs and outputs to tracks.