Adobe is aware that you may see an error message the first time you launch a Creative Cloud application on the latest versions of Mac OS High Sierra. This is due to some 32-bit components that we are working to address in a future Creative Cloud update. Please note that no action is required from you at this time and your applications will still run as normal.
Adobe has tested the latest versions of Adobe Creative Cloud applications for reliability, performance, and user experience when installed on Intel-based systems running macOS High Sierra (version 10.13). The latest versions of all Creative Cloud products are compatible.