You can print more than one page of a PDF onto a single sheet of paper. Printing multiple pages per sheet is also called N-up printing (such as 2-up or 6-up). You can specify how the pages are ordered, either horizontally across the page or in vertical columns.
Choose File > Print.
From the Page Scaling pop-up menu, select Multiple Pages Per Sheet.
From the Pages Per Sheet pop-up menu, select a value.
From the Page Order pop-up menu, select Horizontal, Horizontal Reversed, Vertical, or Vertical Reversed: